A few weeks ago I did a post and case review on the application of a quantitative approach to acid base interpretation. Click the picture below to check it out.
I wanted to expound on this a little more and discuss my thoughts on when it makes sense to give sodium bicarbonate to a patient in a metabolic acidosis.
For a detailed explanation of the Stewart approach check out EMCrit's series here.
Before you listen, here is a picture of the Gamble-Gram. Visualize this while conceptualizing the concept.